Global US Market Study on Sodium Starch Glycolate Industry- Applications and Competitive Analysis to 2024
Sodium starch glycolate is the sodium salt of carboxymethyl ether. It is white to off-white, odorless, tasteless, and free-flowing powder. It is produced by cross-linking and carboxy methylation of potato starch. It can also be manufactured from other starch foods such as corn, wheat, and rice. Sodium starch glycolate is practically insoluble in water and insoluble in most organic solvents. It exists in the form of oval, rounded, irregularly shaped, or spherical granules. These granules exhibit considerable swelling upon contact with water. Based on the empirical formula and molecular weight, sodium starch glycolate can be classified into two types: type A and type B. Based on pH value, it is classified into three types that include type C. Type A and Type B are sodium salts of cross-linked, partly O-carboxymethylated potato starch. On the other hand, type C is formed as sodium salt of partly O-carboxymethylated starch, cross-linked by physical dehydration. Type A, B, and C can be differentiated from each other by checking their pH, sodium, and sodium chloride content. Starch is carboxymethylated by reacting it with sodium choloroacetate in an alkaline, non-aqueous medium, usually denatured methanol or ethanol. This is then followed by neutralization of citric acid, acetic acid, and other acids.
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Sodium
starch glycolate is widely used in pharmaceuticals, as a disintegrant, in the
formation of tablets and capsules. It absorbs water rapidly, which leads to
fast disintegration of granules and tablets. Sodium starch glycolate dissolves
better, which makes it easier for the body to absorb medication. It can also be
used as gelling and suspending agent. The usage of sodium starch glycolate in
the formation of tablets and capsules involves either wet granulation or direct
compression. In higher concentration, it can be used as a dissolution acing
agent. Sodium starch glycolate can be more effective when used as an
intragranular or extragranular disintegrant or when equally divided between
intragranular and extragranular locations. Sodium starch glycolate does not
have any side-effect. However, depending on the source, it can cause adverse
effects on certain individuals. People with allergy to corn or with celiac
disease may experience adverse effects. Tablets or capsules that are prepared
using sodium starch glycolate have excellent storage properties, due to its
physical properties such as stability and hygroscopic nature. In order to
prevent caking, sodium starch glycolate should be kept in a well-closed
container. This can protect it from changes in temperature and humidity. One of
the key characteristics of sodium starch glycolate is that its physical
properties remain the same for up to 3 years, if handled and stored at a
moderate humidity and temperature.
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Europe and
North America regions dominate the global
sodium starch glycolate market, followed by Asia Pacific. This growth
of the market is attributable to application of sodium starch glycolate in
pharmaceuticals. Countries such as the U.S., Switzerland, China, and India have
large-sized pharmaceutical companies. Technological advancements for using this
product is increasing day by day as medical industry have wide applications
globally. Rest of the World held minimum share of the global market in the last
few years. However, the market in the region is expected to expand during the
forecast period.
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Some of
the key players operating in the sodium starch glycolate market are Muby
Chemicals, Shree Chemicals, DFE Pharma, Patel Chem Specialties Pvt. Ltd., and
Prachin Chemical.
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